Similarly, siblings with an initial diagnosis of ALGS were found to have a pathogenic variant in the NEK8 gene, which is commonly mutated in renal‐hepatic‐pancreatic‐dysplasia 2 (RHPD2) and in nephronophthisis (NPHP9), and resulted in a reclassification of the disease to encompass a spectrum of disorders that involve NEK8 pathogenic variants rather than ALGS (Rajagopalan et al., 2016). This evidence concerns the gene NEK8 and nephronophthisis.