Moreover, there were several researches implied that the mechanism of lncRNA MALAT1 might be associated with human diseases, such as MALAT1 could accelerate cell proliferation in gastric cancer via modulating SF2/ASF [11], adjust cancer stem cell (CSC) activity and radioresistance [12] and attenuate the development of renal cancer cells [20]. The gene discussed is SRSF1; the disease is renal carcinoma.