RT-qPCR was employed to evaluate lncRNA MALAT1 expression in HTN patients and healthy people to observe the level of lncRNA MALAT1 in HTN patients, the results of which showed that the lncRNA MALAT1 expression of HTN patients was up-regulated compared with healthy controls, suggesting that MALAT1 was highly expressed in the serum of HTN patients (P < 0.05; Figure 1A). Here, MALAT1 is linked to hypertensive disorder.