Sherlock analysis for the moderate centrilobular GWAS results and GTEx eQTL data from fibroblasts, lung tissue, and whole blood confirmed TGFB2 as a colocalization target for moderate centrilobular emphysema in fibroblasts, and a total of nine colocalizing genes or transcripts were identified at a p-value<1×10−4 (Supplementary file 1 Table 8). This evidence concerns the gene TGFB2 and pulmonary emphysema.