PKM and neoplasm: PKM2 is normally present in the cytoplasm by a form of homotetramer and functions as a metabolic kinase with high catalytic activity.8 In addition, a dimeric PKM2 form has been recently confirmed in cell nucleus, while it works as a protein kinase stimulating transcription to regulate the growth, survival and metastasis of tumour cells.8, 28 In our study, we discovered that β‐elemene suppressed PKM2 translocating into the nucleus.