IL22 and autoimmune disease: A broad variety of lymphocytes secrete IL‐22, including Th17, Th22, and NK cells, neutrophils, and innate lymphoid cells.6 The biological effects of IL‐22 are mediated by the IL‐22‐IL‐22R pathway.7 Its involvement has been reported in many autoimmune diseases, including protective, pathogenic, and dual effects.