Injection of recombinant IL‐35 or IL‐35+ Breg cells into experimental autoimmune uveitis mice inhibited the response of effector T cell 17 (Th17) and effector T cell 1 (Th1) cells and induced Foxp3+ Treg cells to improve inflammation.22 Therefore, we assumed that the decrease observed in serum IL‐35 levels was correlated with the decrease in Breg cells in our study and that this might indicate that IL‐35 plays a very important role in NMOSD. Here, FOXP3 is linked to autoimmune uveitis.