It is important to note, that mice that express catalytically inactive SHIP2 survive longer than 18 months and show no signs of tumour development,128 and neither do mice depleted of SHIP2.106 These data increase the prospects of SHIP2 as a potential cancer treatment target in specific types of cancer in which SHIP2 is overexpressed or overactivated. The gene discussed is INPPL1; the disease is neoplasm.