EDNRA and myocardial infarction: As shown in Figure 10(b) by ELISA detection, ETA protein expression in cardiac tissues of MI rats was significantly higher than that in sham groups (4wk, P<0.05 and 6wk, P<0.01), but was evidently reduced in XJEK (2, 4 and 6wk, P<0.05) or Fosinopril (2wk and 4wk, P<0.05, 6wk, P<0.01) treatment for 2, 4, and 6wk (Figure 10(b)).