SPHK1 and intestinal disorder: Pparg showed the highest degree (degree = 39), along with Sphk1 (Sphingosine kinase 1, degree = 31), Klf5 (Kruppel-like factor 5, degree = 19), and Akr1b10 (Aldo-keto reductase family 1 member B10, degree = 19), demonstrating the potential therapeutic effect of each drug contained in SLBZS for combating intestinal disease via modulation of these relevant proteins.