BRCA1 and breast cancer: For Colombia, Torres et al. [9], established the prevalence of three founder mutations for this population “Profile Colombia”, however, the results found in this study suggest the existence of other different founder mutations (p.Thr790Ala, p.Arg959Lys, p. Glu1345Lys for BRCA1 and p.Leu771Phe, p.Asn818Lys, p.Val859Ser * 22, p.Lys1032Ile for BRCA2) that may be modulating the development of breast cancer in the country.