In the nephrotoxic nephritis (NTN) model, Pod-Cd9lox/lox mice had similar renal injury as control mice, as shown by ACR (807.7 ± 184.2 mg.mmol−1 vs. 864.2 ± 242.3 mg.mmol−1 in Pod-Cd9wt/wt vs. Pod-Cd9lox/lox mice), BUN (51.96 ± 9.46 mg.dL−1 vs. 49.37 ± 5.01 mg.dL−1 in Pod-Cd9wt/wt vs. Pod-Cd9lox/lox mice), and crescentic glomerular lesions (27.67 ± 2.36% vs. 30.00 ± 2.63% of crescents in Pod-Cd9wt/wt vs. Pod-Cd9lox/lox mice) (Supplementary Fig. 6), thus supporting the idea that podocyte CD9 expression is not involved in crescent formation in CGN. This evidence concerns the gene CD9 and childhood gender nonconformity.