In addition to common clinical [15] and laboratory parameters that are used to subjectively predict bacteremia and sepsis in neonates, acute phase reactants such as C-reactive protein (CRP) and procalcitonin (PCT) [16, 17] are being investigated; however, they have limitations [17] and are either not routinely measured or quickly available in most hospitals. The gene discussed is CRP; the disease is bacterial infectious disease with sepsis.