Consistent with RNA-seq data, the expression of SLN, TAC1, MYH8, and PGAM2 were down-regulated, whereas SDRC7, KRT16, S100A9, IL36G, and FABP9 were up-regulated in both blood (Animal #9, #11, and #12) and skin (Animal #6, #7, and #8)-induced tumours relative to normal skin controls (Figure 4B). The gene discussed is KRT16; the disease is neoplasm.