Regarding the homeostasis model assessment of insulin resistance (HOMA-IR), a parameter that estimates insulin sensitivity considering the relation between fasting insulin and fasting glucose, was—on average—clearly above the cut-off level of two [30], indicating insulin resistance and not different among the testing days (placebo: 2.95; low dose: 2.80; high dose: 2.96; six week intervention: 2.84; Figure 2). The gene discussed is INS; the disease is Insulin resistance.