ENG and Alzheimer disease: Figure 5a show images of microglia (yellow–Merge) demonstrating colocalization of CD105 (red) with IBA-1 (green). Figure 5b shows how a strongly-stained CD105-positive microglia with a highly-activated morphology (red) occupies the cell body with the IBA-1-staining (green) being more restricted, but where colocalization (yellow) can be seen (Figure 5b Merge). Figure 5c reverses the detection colors, but in this severe AD case, there are varying degrees of colocalization of CD105 immunoreactivity (green) with IBA-1 (red) as yellow in all cells (Figure 5c).