Consistent with the role of ΔNp63α as a regulator of FGFR2 [64], further analyses revealed the fibroblast growth factor (FGF) signaling pathway, specifically FGFR2, was shown to be significantly upregulated by ΔNp63α and required for tumor progression to occur in this model [95]. The gene discussed is FGFR2; the disease is neoplasm.