Furthermore, we revealed that activation of the phosphorylation of dynamin-related protein 1 (Drp1), the major mitochondrial fission protein, was related to seizure-induced neuronal damage and that lessened p-Drp1 expression could reduce mitochondrial fission, as well as decrease mitochondrial dysfunction and oxidation, which offer a protective strategy against seizure-induced hippocampal neuronal damage in the hippocampus following status epilepticus [15]. Here, DNM1L is linked to status epilepticus.