Given the importance of PPARβ/δ and the transcription factors NF-κB and Nrf2 effects for the CAD patients - the Nrf2 orchestrating the production of antioxidant and phase 2 detoxifying enzymes being considered a protective factor against both oxidative stress and inflammation,46 PPARβ/δ promoting cardioprotection42 and NF-κB regulating inflammation12 - a better understanding of how they are expressed in CAD patients is useful so that strategies can be used in an attempt to modulate these transcription factors. This evidence concerns the gene PPARD and coronary artery disorder.