RHOA and hepatocellular carcinoma: Next, we divided HCC patients from TCGA into a high-risk group and a low-risk group according to the optimal cutoff value of RhoA expression mentioned before to explore the relationships of RhoA expression with different clinicopathological parameters, and we only found that male patients had significantly higher RhoA gene expression levels than female patients (Table 1, Supplementary Table 1, and Figure 3A).