ALB and neoplasm: For example, interstitial secreted protein, acidic and rich in cysteine, in PDAC has a high affinity for albumin, which enriches albumin‐bound paclitaxel in proximity to PDAC and enhances the delivery of paclitaxel into the tumor microenvironment.61 In a phase III study that enrolled patients with advanced PDAC, the combination of albumin‐bound paclitaxel and gemcitabine improved survival when compared with gemcitabine alone, while the addition of paclitaxel had no effect.62 Therefore, CAR‐T cells carrying albumin may acquire enhanced infiltrating and tumor‐killing capability.