GDF5 and acromesomelic dysplasia: GDF5 mutations are linked with various rare skeletal disorders such as type A2 and type C of brachydactyly (Polinkovsky et al., 1997; Seemann et al., 2005), grebe type of chondrodysplasia (Thomas et al., 1997), Hunter‐Thompson type of acromesomelic dysplasia, (Thomas et al., 1996), and DuPan syndrome (Faiyaz‐Ul‐Haque et al., 2002).