To determine the in vivo protective effects of LX/IL-24-infected tumor vaccine, C57BL/6 mice were immunized with PBS, irradiated B16-F10 (B16), LX/RFP-infected B16-F10 cells (B16-LX/RFP), or LX/IL-24-infected B16-F10 cells (B16-LX/IL-24). The gene discussed is IL24; the disease is neoplasm.