EZH2 and acute lymphoblastic leukemia: We have observed that ETP and immature T-ALL subtypes were enriched with alterations in epigenetic regulators EZH2, SUZ12, and PHF6 (p < 0.001 and p = 0.02, respectively), whereas these alterations were less frequently found in the late cortical and mature T-ALL subtypes (p = 0.013).