KRAS and hepatocellular carcinoma: However, KT11 treatment did not increase the incidence of HCC in the kras/L-ARKO zebrafish in comparison with the kras/L-ARKO zebrafish treated with Dox alone, and the incidence of HCC in adult kras/L-ARKO zebrafish was lower than that in adult kras fish with or without KT11 treatment (Fig. 6A,B).