Interestingly, NKG2D-Ls (ULBP1, MICA/B and ULBP2) have been detected in cervical cancer cell lines [47,48] and their expression in tumor tissues is an indicator of good prognosis in patients with cervical cancer, suggesting that ligand-expressing cells can be targeted by NKG2D receptor-expressing immune cells in vivo [49]. The gene discussed is MICA; the disease is cervical carcinoma.