Considering that most of the αA-CTXs identified by RT-PCR from C. princeps are predicted to target α7 nAChRs (but also α3β2 and other neuronal subtypes) [14], and the potential implications of α7 nAChRs antagonists to treat cancer, and cardiac and renal disorders [22], in this study we aimed to detect, purify, and characterize, toxins with activity at human α7 nAChRs from the venom of this species. The gene discussed is TEAD1; the disease is cancer.