Colorectal adenoma samples of p4, p6, p7, p10, p11, p12 exhibit mutations in APC, while p4, p13, and p14 show mutations in CTNNB1. p6 and p11 show mutations in FAM123B. In addition, CRC samples of p5, p10, and p14 reveal the mutation in APC. As for CRC samples of p4, p5, and p10, the mutations of the SOX9 gene were found. This evidence concerns the gene CTNNB1 and colorectal adenoma.