On contrast, significantly lower number of IFN-γ-producing, T-bet and CXCR3-expressing Th1 cells (p < 0.01; Figure 6H,I), and IL-17-producing and CCR6-expressing Th17 cells (p < 0.01; Figure 6J,K), accompanied by significantly reduced serum levels of IFN-γ and IL-17 (p < 0.05; Figure 6L), were observed in DSS-treated mice after adoptive transfer of WT DCsLPS, indicating that WT DCsLPS alleviated DSS-induced colitis by suppressing Th1 and Th17 cell-driven inflammatory response in the gut. The gene discussed is CXCR3; the disease is colitis.