LGALS3 and colitis: Keeping in mind that macrophages play important roles in the induction phase of colitis, while T cells are the most important effector immune cells for progression of colon inflammation, herewith, by using clinical data and complementary in vitro and in vivo approaches, we tried to delineate molecular mechanisms, which are responsible for Gal-3-dependent regulation of immune response in the inflamed gut and to determine whether Gal-3 may be used as a valuable biomarker for monitoring UC progression.