With a median follow-up of 2.1 years (standard deviation (SD), 1.6 years), the median PFS on EGFR-TKI calculated by Kaplan–Meier analysis in the COPD cohort (before PS matching) was 0.62 years, significantly shorter than the non-COPD cohort (0.69 years, p < 0.001; Figure 2). Here, EGFR is linked to chronic obstructive pulmonary disease.