ICAM1 and cystic fibrosis: In a separate study that compared duodenal mucosal specimens from 14 pancreatic insufficiency CF patients, 20 healthy controls, and four non-CF patients with chronic pancreatitis, an increased mononuclear cell infiltrate expressing the intercellular adhesion molecule (ICAM -1), the IL-2 receptor α (CD25), IL-2 and interferon- γ has been observed at the lamina propria level of the duodenal mucosa.