TMBIM6 and carcinoma: Later, different carcinoma cell lines such as MDA-MB 231, MCF7, DU145, and HT1080 were transfected with P9-TMBIM6-HA or P9-(mSp1d, mSp1p)-TMBIM6-HA and treated with anticancer agents paclitaxel and cyclophosphamide at different concentration for 24 h, then cell viability was assessed.