ART4 and infection: Thereafter, the same authors documented that, while the envelope of the laboratory strain AD169 virions contains only the gH/gL/gO glycoprotein complex, the AD169 virus with a repaired UL131 gene carries two distinct gH/gL-containing complexes: gH/gL/gO, mediating infection of fibroblasts, and gH/gL/pUL128-131, which is likely to mediate the infection of both epithelial cells and endothelial cells [44].