Whereas LPS, widely used to mimic bacterial infections in vitro, evoked distinct pro-inflammatory responses in HBMEC, expressed by mRNA and protein increases for CXCL5, IL-1α, IL-1β, IL-6, IL-8, MCP-1, MCP-3, and TNF-α, Ureaplasma spp. This evidence concerns the gene IL1B and bacterial infectious disease.