ITGAX and neoplasm: To verify the applicability of our risk score in routine flow cytometry analysis, we correlated the gene expression profile signal of the markers included in the risk score with their mean fluorescence intensity (MFI) in the 16 DLBCL cell lines, due to the absence of a high enough number of primary tumor cell samples for a statistically robust analysis, and found a significant correlation for all of them (r = 0.68 for BCL2, r = 0.59 for BCL6, r = 0.80 for LAIR1, and r = 0.84 for CD11c, p < 0.05, Supplementary Figure S6).