TNFRSF8 and synovial sarcoma: A retrospective cohort study suggested that a focus score of ≥3 in a labial salivary gland biopsy was an independent predictor of the development of non-Hodgkin lymphoma in patients with primary SS.[16] In addition, a germ center-like structure could be referred to as a sign of developing malignant lymphoma in SS patients.[17] It is conceivable that examination of excessive CD30 expression in lacrimal gland and conjunctival tissues may become an additional option to predict the initiation and propagation of ML.