CD30 has been recognized as a marker of the malignant Hodgkin and Reed-Sternberg cells in HL.[15] Therefore, CD30+ cells on the ocular surface and in lacrimal glands may be an important predictor of malignant lymphoma, and thereby great caution should be accorded to long-term follow-up SS patients. This evidence concerns the gene TNFRSF8 and synovial sarcoma.