ELN and invasive carcinoma: They only mentioned that the amount of elastin in the stroma of OSCC was less as compared to collagen, and no details were given regarding the pattern and morphology of elastic fibers in various grades of OSCC.11 The study by Ma described a primary increase followed by a decrease in the amount of elastic fibers with increasing grades of carcinoma.19 In contrast, a study performed by Zhang et al. revealed a decrease in elastic fibers with neoplastic progression from epithelial atypia to early invasive carcinoma.20