INS and Hypoglycemia: In this exploratory post hoc analysis of hypoglycemia as a function of HbA1c in patients with T1D receiving sotagliflozin or placebo in combination with optimized insulin therapy, level 1 hypoglycemia event rates were 22% lower with both doses of sotagliflozin compared to placebo, and level 2 was 28% and 30% lower with sotagliflozin 200 and 400 mg, respectively.