Downregulated ADAMTS8 in some cancers including NSCLC (Heighway et al., 2002; Huang et al., 2019; Masui et al., 2001; Porter et al., 2004; Rodriguez-Rodero et al., 2013; Zhao et al., 2018) is associated with poorer prognosis (Drilon et al., 2014; Li et al., 2015; Porter et al., 2006). This evidence concerns the gene ADAMTS8 and non-small cell lung carcinoma.