LAP3 and infection: Identification of chitinases shown to target at L. maculans at the apoplastic space of pre-symptom stage cotyledons in previous studies during the incompatible interaction (Legrand et al., 1987; Profotová et al., 2007) and kunitz trypsin inhibitors that degrade the peptidases secreted by L. maculans during the early infection stage (Sonah et al., 2016) implicates the direct deployment of enzymatic force by LepR3 and Rlm2 to fend off L. maculans during in planta invasion (Figure 5).