Adipocytokine signaling pathway, regulation of lipolysis in adipocytes, negative regulation of fatty acid beta-oxidation, positive regulation of lipid biosynthetic process, non-alcoholic fatty liver disease, glucose metabolic process, glucose homeostasis, insulin resistance, inflammatory response, T cell receptor signaling pathway, B cell receptor signaling pathway, TNF signaling pathway, AMPK signaling pathway. Here, INS is linked to metabolic dysfunction-associated steatotic liver disease.