It would have been of interest to measure Css, min levels of stiripentol given that many children with Dravet syndrome would also be taking this medication and stiripentol is metabolized by CYP2C19 and CYP3A4 isoenzymes. The gene discussed is CYP2C19; the disease is encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.