• Probable CTE group has at least one positive CTE biomarker such Tau PET imaging vs. possible have progressive CTE course with any biomarker testing vs. in the unlikely CTE group, TES diagnosis not satisfied or negative Tau imaging or both• If the clinical presentation also included motor signs such as parkinsonism, the modifier “with motor features” was also added. This evidence concerns the gene MAPT and Parkinsonism.