SLC16A3 and cancer: Additionally, transporters including MCT-1 (SLC16A1) and MCT-4 (SLC16A3) mediate the uptake of lactate and branched-chain keto acids (Kennedy and Dewhirst, 2010; Silva et al., 2017), SLC7A11 for cysteine (Huang et al., 2005), and ASCT2 for glutamine (Cormerais et al., 2018), facilitating the uptake of alternative fuels by cancer cells.