MAPT and frontotemporal dementia: The two most common FTLD neuropathologies are frontotemporal lobar degeneration with inclusions of the protein tau (FTLD-Tau) and frontotemporal lobar degeneration with inclusions of the transactive response DNA-binding protein of 43 kDa (FTLD-TDP) (Mackenzie et al., 2010; Irwin et al., 2015).