K-M survival curves showed that the survival rate of the high risk group was significantly lower than that of the low risk score group (Fig. 5d) and patients with high risk score can be characterized as high expression of TPST1 and P3H4 (Fig. 5e), which together were in close agreement with the results observed in the TCGA dataset, suggesting again the importance of the risk score model in prognosis prediction of BLCA. This evidence concerns the gene P3H4 and bladder transitional cell carcinoma.