HDL functions the efflux of cholesterol in macrophage-derived foam cells under angiothelium through ATP-binding cassette transporter G1 and ATP-binding cassette transporter A1 pathways, which has antiapoptotic, anti-inflammatory, and antioxidant effects against atherosclerosis.20 Therefore, patients with MetS are more prone to develop vascular lesions, which result in dysfunction of coagulation and higher blood loss during operations. Here, ABCA1 is linked to metabolic syndrome.