A previous study showed that RND3 increased the apoptosis of U87 glioblastoma cells.23 RND3 overexpression induced decreases in the phosphorylation of glioblastoma protein and expression of cyclin D1, resulting in inhibition of U87 cell cycle progression.23 However, the authors' observations of RND3 on U87 glioblastoma cells were focused only at the cellular level. This evidence concerns the gene RND3 and glioblastoma.