Statistical analysis showed that high expression of TP73 was markedly associated with clinical stage (I–IIA vs. IIB–IV, P<0.001, Table 2), lymph node metastasis (Absent vs. Present, P<0.001, Table 2), distant metastasis (Absent vs. Present, P=0.004, Table 2), histological type (adenocarcinoma vs. squamous cell carcinoma, P=0.001, Table 2), and histological grade (well vs. moderately/poorly, P<0.001, Table 2). The gene discussed is TP73; the disease is squamous cell carcinoma.