Positive staining for CAM6/CAM5/E-cad and E-cad/ZEB1 was detected in Her2+ER−PR− (Her2-positive, estrogen receptor–negative, and progesterone receptor-negative) breast cancers more frequently than in other tumors (Fig 9B and Tables S2, S3, S4, S5). The gene discussed is ESR1; the disease is breast cancer.