CAM5, CAM6, E-cad, and ZEB1 expressions mediating the Ehi and E/M states were also significantly attenuated in DCISCAF1cy extracted from DCIS tumors expressing CXCR4- or TβRII-shRNA admixed with CAFs (Figs 7E, G, H, and S6B). This evidence concerns the gene CXCR4 and ductal breast carcinoma in situ.