CAM5, CAM6, E-cad, and ZEB1 expressions mediating the Ehi and E/M states were also significantly attenuated in DCISCAF1cy extracted from DCIS tumors expressing CXCR4- or TβRII-shRNA admixed with CAFs (Figs 7E, G, H, and S6B). The gene discussed is ZEB1; the disease is ductal breast carcinoma in situ.