The Ehi and E/M tdTomato+ tumor cell proportions were also significantly increased in CAF-containing tumors relative to E-cadhiZEB1hi tumor cells (Figs 1D and , S1G), reflecting the well-known inverse relationship between E-cad and ZEB1 expressions (Eger et al, 2005; , Sanchez-Tillo et al, 2010). The gene discussed is ZEB1; the disease is neoplasm.