CD4 and systemic lupus erythematosus: There was no significant difference between the percentages of IL-22-producing CD134+CD4+ T-cells in active SLE patients as compared to inactive SLE patients (8.0 ± 8.4% vs. 10.9 ± 9.2%; p = 0.63) and active SLE patients as compared to HC (8.0 ± 8.4% vs. 19.0 ± 11.8%; p = 0.06).