CD274 and non-small cell lung carcinoma: To evaluate the effect of PD-L1 knockdown on the migratory and invasive abilities of NSCLC cells in vivo, stable PD-L1 knockdown HCC827 cells (Sh-PD-L1–1) or negative control cells (Sh-NC) were injected into the tail veins of BALB/c athymic nude mice.